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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2014 Mar;73(3):253–261. doi: 10.1097/NEN.0000000000000048

Figure 6. Arx−/Y mice lack TH expression in the ZI’s A13 dopaminergic subnucleus.

Figure 6

Representative coronal sections, stained for tyrosine hydroxylase (TH), are shown for wild type (left panel), Arx(GCG)7/Y (middle panel) and Arx−/Y (right panel) mice. The approximate boundaries of the A13 subnucleus of the zona incerta (ZI) are demarcated by dotted white lines. TH expression is apparent in this region for both wild type and Arx(GCG)7/Y, but is absent from Arx−/Y sections. Other areas of expected TH staining, such as the arcuate nucleus (*) and the retrochiasmatic projection fibers from the median forebrain bundle (arrow) maintained TH expression. Scale bar = 500 µm.