Table 2.
Dusps genes expression profile from Dusp3-knockout versus WT Matrigel plugs
| Gene name | Protein names | Ratio Dusp3 -KO/WT | P value |
|---|---|---|---|
|
Typical Dusps
| |||
|
Dusp1 |
MKP1 |
0.60 |
0.041* |
|
Dusp2 |
PAC-1 |
1.0 |
0.96 |
|
Dusp4 |
MKP2 |
0.48 |
0.18 |
|
Dusp5 |
DUSP5; hVH3; B23 |
NP |
|
|
Dusp6 |
MKP3 |
1 |
0.9 |
|
Dusp7 |
MKPX |
0.9 |
0.6 |
|
Dusp8 |
DUSP8 |
0.97 |
0.88 |
|
Dusp9 |
MKP4 |
ND |
|
|
Dusp10 |
MKP5 |
1.5 |
0.23 |
|
Dusp16 |
MKP7 |
1.2 |
0.33 |
|
Styxl1 |
MK-STYX |
ND |
|
|
Atypical Dusps
| |||
|
Epm2a |
Laforin |
ND |
|
|
Dusp3 |
VHR |
ND |
|
|
Dusp11 |
PIR1 |
1 |
0.75 |
|
Dusp13 |
MDSP; TMDP; DUSP13 |
1.8 |
0.38 |
|
Dusp14 |
MKP6 |
0.84 |
0.51 |
|
Dusp15 |
VHY |
1.1 |
0.56 |
|
Dusp18 |
LMW-DSP20 |
0.54 |
0.11 |
|
Dusp319 |
SKRP1; LMW-DSP3 |
1.3 |
0.057 |
|
Dusp21 |
LMW-DSP21 |
ND |
|
|
Dusp22 |
JSP-1; JKAP; MKPX; VHX |
1.4 |
0.078 |
|
Dusp23 |
LDP-3; VHZ |
0.85 |
0.04* |
|
Dusp26 |
MKP8, NEAP |
1.3 |
0.71 |
|
Dupd1 |
DUPD1 |
2.5 |
0.18 |
|
Dusp28 |
VHP |
1.1 |
0.31 |
| Styx | STYX | 1.1 | 0.43 |
Data presented in this table are extracted from a genome-wide microarray dataset obtained using Illumina’s multi sample format Mouse WG-6 V2 BeadChip. Data are presented as the ratio of the average values obtained from 2 pools of 3 Dusp3-knockout each on 2 pools of 3 WT mice each and the corresponding p-value. (*p < 0.05 determined using unpaired student’s t test). ND: not detected. NP: no probe/not present on the microarray chip.