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. Author manuscript; available in PMC: 2014 May 29.
Published in final edited form as: Pathophysiology. 2012 Mar 22;20(1):59–69. doi: 10.1016/j.pathophys.2012.02.003

Figure 1. Expression of CC and CXC chemokines and chemokine receptors in MIE (medically intractable temporal lobe epilepsy) and trauma.

Figure 1

Immunohistochemistry or confocal microscopy of temporal lobe (TL) and hippocampus (H) using the following antibodies: (A) RANTES (TL, 40X); (B) RANTES/NeuN (TL, 100x); (C) RANTES green /DAPI (TL, confocal microscopy 100x) (D) RANTES/GFAP (H, 40x); (E) MIP -1 β (40x); (F) MIP-1α(40x); (G) RANTES (Trauma cortex, 20x); (H) SDF-1(H,40x); (I) CCR5 (20x); (J) CCR1 (40x); (K) CXCR4 (40x); (L) CCR5 (Trauma cortex, 40x). Note RANTES expression in neuronal nuclei (A-D) but cytoplasmic expression of MIP-1α and MIP-1β extending into the neuropil (E, F).