Figure 1.

Daily fecal egg output trend in chronically infected baboons before and after vaccination with Sm-p80 formulated with a Toll-like receptor 4 agonist–based emulsion, glucopyranosyl lipid adjuvant (GLA)–SE. The fecal samples were collected starting 6–8 weeks after infection from each baboon belonging to adjuvant-only control (GLA-SE) or vaccinated (Sm-p80–GLA-SE) groups. The numbers of eggs in feces were monitored every 3–5 days, starting 72 days after infection and continuing until the animals were euthanized.