. Author manuscript; available in PMC: 2014 May 29.

Published in final edited form as: Chem Res Toxicol. 2011 Mar 17;24(4):494–504. doi: 10.1021/tx100328r

Table 4.

Chromosomal density of putative DREs^a (per Mbp^b) within the 10kb upstream, 5′ and 3′ UTRs, and CDS regions^c of RefSeq sequences in the human, mouse and rat genomes.

Chromosome	Human				Mouse				Rat
Chromosome	10kb upstream	5′ UTR	CDS	3′ UTR	10kb upstream	5′ UTR	CDS	3′ UTR	10kb upstream	5′ UTR	CDS	3′ UTR
1	35.8 ^d	27.5	27.3	22.1 ^d	39.8	30.6 ^d	29.6	32.8	43.3 ^d	52.6	41.7	34.6 ^d
2	62.2 ^e	40.2	27.1	26.2	38.8	41.2	34.0	36.1	49.7	34.9 ^d	37.1 ^d	36.2 ^d
3	51.4	18.1 ^d	22.9 ^d	24.8	41.9	42.6	31.2	40.3	48.4	33.6 ^d	44.0	61.9
4	57.4 ^e	29.2	28.6	27.5	49.4 ^e	46.1	37.2	43.1	42.6 ^d	36.1 ^d	38.2	42.9 ^d
5	54.0	43.8	28.9	30.4	49.1 ^e	58.7 ^e	38.8 ^e	34.0	53.7	53.4	43.5	50.8
6	41.4	28.4	26.8	23.8	35.0 ^d	37.7	32.4	38.5	49.2	54.6	44.7	39.1 ^d
7	49.9	32.5	27.2	30.4	36.5	41.6	39.1 ^e	44.9	60.2 ^e	49.9	49.0	51.8
8	52.2	27.6	27.0 ^d	29.7	48.7 ^e	33.6 ^d	39.6 ^e	50.4 ^e	50.5	49.1	45.2	50.4
9	46.1	28.9	30.3	35.1 ^e	40.2	42.9	36.4	44.8	47.4	51.5	41.2	66.4 ^e
10	50.8	29.4	23.2	24.5	40.3	33.6 ^d	34.2	40.1	54.3	66.4 ^e	51.6	48.7
11	34.9 ^d	37.4	27.7	24.4	48.2 ^e	52.0 ^e	39.5 ^e	47.2 ^e	48.8	33.9 ^d	44.8	77.6 ^e
12	42.4	27.4	26.0 ^d	16.4 ^d	42.3	38.5	36.4	50.9 ^e	77.7	69.1 ^e	84.5 ^e	61.1
13	84.8 ^e	47.6 ^e	31.8	48.1 ^e	34.0 ^d	36.2	30.3	37.6	42.5 ^d	54.6	42.6	55.2
14	56.7 ^e	32.7	26.2 ^d	30.2	40.6	40.7	31.7	40.6	42.0 ^d	55.3	42.3	67.1 ^e
15	47.0	27.0 ^d	34.1	27.3	48.4 ^e	41.9	39.1 ^e	41.4	46.5	42.7 ^d	39.3	73.3 ^e
16	51.6	41.3	49.4 ^e	47.9 ^e	39.8	40.9	29.9	41.3	65.1	63.3 ^e	43.9	65.9 ^e
17	33.8 ^d	60.5 ^e	31.5	18.2 ^d	46.4 ^e	46.4	41.9 ^e	39.8	46.3	53.8	41.5	37.4 ^d
18	76.0 ^e	30.1	35.7	35.1 ^e	40.4	38.3	37.8	37.0	53.8	48.8	39.3	25.2 ^d
19	25.0 ^d	50.9 ^e	52.7 ^e	27.6	43.0	51.3 ^e	37.3	38.4	55.4	48.9	52.4	58.1
20	49.9	33.7	37.0 ^e	20.7 ^d					64.0 ^e	58.9 ^e	73.7 ^e	78.3 ^e
21	41.6	19.2 ^d	32.5	21.7 ^d
22	42.9	51.4 ^e	41.3 ^e	28.3
X	26.8 ^d	25.0 ^d	21.4 ^d	12.9 ^d	20.5 ^d	19.8 ^d	14.8 ^d	14.5 ^d	31.0 ^d	30.3 ^d	23.2 ^d	34.4 ^d
Y^f	45.2	98.9 ^e	42.6 ^e	16.7 ^d	26.7 ^d	84.1 ^e	13.3 ^d	0.0 ^d

Mean density	48.3	37.0	31.6	27.1	40.5	42.8	33.5	37.8	51.1	49.6	45.9	53.2
Std. Dev	13.6	16.8	8.0	8.5	7.3	12.5	7.4	11.4	9.9	10.9	12.6	15.3

putative DREs defined as the 19 bp DRE centered core containing sequence with a MS score ≥ 0.8473

Mbp = million basepairs

regions are defined using the genomic locations in the refGene database from the UCSC Geriome Browser

putative DRE density is less than the lower limit of the 99% confidence interval of the mean

putative DRE density is greater than the upper limit of the 99% confidence interval of the mean

no sequence data for chromosome Y is available in rn4 build of the rat genome