Table 1.
Molar Percent of Lipids in Each Microbubble Formulation
Lipid shell (mol %) | Total lipid/vial (mg) |
||||||||
---|---|---|---|---|---|---|---|---|---|
Microbubble | Surface | DPPC / DSPC | DPPA / DSPA | MPEG5000 −DPPE / −DSPE |
DSTAP | ||||
Definity® | Neutral | 82 | - | 10 | - | 8 | - | - | 1.3 |
RN16 | Neutral | 78 | - | 10 | - | 12 | - | - | 1.3 |
RN18 | Neutral | - | 82 | - | 10 | - | 8 | - | 1.2 |
RC5k | Cationic | - | 74 | - | - | - | 5 | 21 | 1.3 |