Table 2.

Potential time points early in behavioral weight loss treatment to evaluate weight loss progress among women with obesity and depression (N=75)

Week of treatment	Weight loss not on target, N (%)	Weekly attendance, N (%)	Drop-out, N (%)	Clinically significant weight loss at 6 months, by early-treatment weight loss
				Se, %	Sp, %	5% or greater weight loss at 6 months among those whose early-treatment weight loss was on target N (%)	5% or greater weight loss at 6 months among those whose early-treatment weight loss was not on target N (%)	Crude RR (95% CI)	Adjusted RR (95% CI)
Week 2	33 (44)	65 (87)	2 (3)	56	72	23 (55)	9 (27)	2.01 (1.08–3.74)	2.40 (2.32–4.35)a
Week 3	32 (43)	64 (85)	5 (7)	53	72	23 (54)	9 (28)	1.90 (1.02–3.54)	2.32 (1.25–4.29)b
Week 4	35 (47)	58 (77)	7 (9)	60	72	23 (58)	9 (26)	2.24 (1.20–4.17)	2.02 (1.05–3.92)c
Week 5	40 (53)	54 (72)	7 (9)	70	69	22 (63)	10 (25)	2.51 (1.39–4.55)	2.51 (1.39–4.55)
Week 6	44 (59)	54 (69)	7 (9)	77	66	21 (68)	11 (25)	2.71 (1.54–4.77)	2.71 (1.54–4.77)
Week 7	45 (60)	48 (64)	7 (9)	77	63	20 (67)	12 (27)	2.50 (1.45–4.32)	2.85 (1.60–5.09)d
Week 8	47 (63)	52 (69)	8 (11)	84	66	21 (75)	11 (23)	3.20 (1.83–5.61)	3.20 (1.83–5.61)

Se: sensitvity, i.e., proportion of women failing to achieve 5% or greater weight loss at 6 months who were not on target with their weight loss at a given week early in treatment; Sp: specificity, i.e., proportion of women achieving 5% or greater weight loss at 6 months who were on target with their weight loss at a given week early in treatment.

^aAdjusted for BMI category (class II or III obesity versus overweight or class I obeisty) at treatment initiation;

^bAdjusted for BMI (continuous) at treatment initiation;

^cAdjusted for education (categories);

^dAdjusted for smoking (never versus former smoking)