Table 4.

6-month weight loss in relation to weight loss progress evaluated at week 3 and a subsequent week of behavioral weight loss treatment among women with obesity and depression (N=75)

Weeks of treatment	Weight loss not on target at either week 3 or later week, N (%)	Se, %	Sp, %	Clinically significant weight loss at 6 months, by early-treatment weight loss
				5% or greater weight loss at 6 months among those whose early-treatment weight loss was on target at week 3 and subsequent week, N (%)	5% or greater weight loss at 6 months among those whose early-treatment weight loss was not on target at either week 3 and/or subsequent week, N (%)	Crude RR (95% CI)	Adjusted RR (95% CI)
Weeks 3 & 4	39 (52)	65	66	21 (58)	11 (28)	2.07 (1.17–3.66)	1.82 (0.99–3.36)a
Weeks 3 & 5	41 (55)	70	66	21 (62)	11 (27)	2.30 (1.30–4.07)	2.30 (1.30–4.07)
Weeks 3 & 6	47 (63)	79	59	19 (68)	13 (28)	2.45 (1.45–4.16)	2.45 (1.45–4.16)
Weeks 3 & 7	47 (63)	79	59	19 (68)	13 (28)	2.45 (1.45–4.16)	2.85 (1.60–5.09)b
Weeks 3 & 8	50 (67)	86	59	19 (76)	13 (26)	2.92 (1.74–4.90)	2.92 (1.74–4.90)

Se: sensitvity, i.e., proportion of women failing to achieve 5% or greater weight loss at 6 months who were not on target with their weight loss at a given week early in treatment; Sp: specificity, i.e., proportion of women achieving 5% or greater weight loss at 6 months who were on target with their weight loss at a given week early in treatment.

^aAdjusted for education (graduate, bachelor’s, or HS/some college versus less than HS);

^bAdjusted for smoking (never versus former smoking).