Table 1. Clinical features of patients with colorectal cancer.

	Cancer type	Age	Sex	Locationa	Histological stage	Lamin B2 levela
1	HNPCC	49	Male	R	3	1.4***
2	HNPCC	44	Male	S	4	1.0
3	HNPCC	46	Male	R	1	1.5***
4	HNPCC	44	Male	T	3	2.0***, 1.0b
5	HNPCC	57	Female	A	3	1.3***
6	HNPCC	48	Female	R	3	1.0
7	HNPCC	61	Female	A	2	0.8***
8	Sporadic	67	Male	T	3	0.9*
9	Sporadic	82	Male	A	2	1.2*
10	Sporadic	56	Female	A	3	1.0
11	Sporadic	67	Female	C	3	0.5***
12	Sporadic	41	Female	A	4	0.9
13	Sporadic	60	Male	S	3	1.1
14	Sporadic	67	Male	D,S	4	1.0
15	Sporadic	82	Male	D	2	1.0

Abbreviations: A, ascending colon; C, cecum; D, descending colon; R, rectum; S, sigmoid colon; T, traverse colon. Asterisks indicate significant differences between cancer and normal epithelial cells, calculated by Student's t-test (*P<0.05; ***P<0.001).

^aLevels of lamin B2 expression in cancer cells are relative to the adjacent normal epithelial cells (see Supplementary Figure S5).

^bTwo distinct tissues from the same patient were examined for lamin B2 expression.