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. 2014 Mar 24;3(3):e95. doi: 10.1038/oncsis.2014.8

Table 3. Significantly enriched Gene Ontology (GO) terms identified by integrated DNA methylation and expression profiling in 8p11-p12-amplified breast tumors.

Category GO term P-value Gene count
Biological process
 GO:0032099 Negative regulation of appetite 8.32E−05 2
 GO:0045671 Negative regulation of osteoclast differentiation 2.48E−04 2
 GO:0045060 Negative thymic T-cell selection 2.48E−04 2
 GO:0008343 Adult feeding behavior 4.93E−04 2
 GO:0006935 Chemotaxis 0.00203 4
 GO:0007281 Germ cell development 0.002871 2
 GO:0006260 DNA replication 0.003236 4
 GO:0007420 Brain development 0.003323 3
 GO:0030335 Positive regulation of cell migration 0.007046 2
 GO:0006366 Transcription from RNA polymerase II promoter 0.014531 3
 GO:0016337 Cell-cell adhesion 0.030651 2
 GO:0008544 Epidermis development 0.042861 2
       
Molecular function
 GO:0043169 Cation binding 0.011569 2
 GO:0008083 Growth factor activity 0.013173 3
 GO:0001104 RNA polymerase II transcription factor activity 0.013842 3
 GO:0005179 Hormone activity 0.021768 2
 GO:0004252 Serine-type endopeptidase activity 0.030247 3
 GO:0006351 Transcription regulator activity 0.038615 2
       
Cellular component
 GO:0005615 Extracellular space 3.46E−05 10
 GO:0005576 Extracellular region 2.89E−04 17
 GO:0043005 Neuron projection 0.002871 2
 GO:0009897 External side of plasma membrane 0.079513 2
 GO:0005634 Nucleus 0.081344 22
 GO:0005794 Golgi apparatus 0.08346 6
 GO:0005768 Endosome 0.096152 2
 GO:0005578 Proteinaceous extracellular matrix 0.107112 3
 GO:0005737 Cytoplasm 0.33593 19