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. Author manuscript; available in PMC: 2014 May 29.
Published in final edited form as: Annu Rev Genet. 2010;44:393–417. doi: 10.1146/annurev-genet-102209-163602

Figure 5.

Figure 5

DNA structures unwound by one or multiple RecQ helicases. The RecQ proteins unwind a diverse set of DNA structures in vitro such as blunt ended DNA (however, not the preferred substrate), 3’ overhangs, forked substrates (such as those that arise during DNA replication), displacement-loops (D-loops, that arise during strand invasion), 4-way junctions (similar to a Holliday junction, HJ), synthetic dHJs (mimicking a recombination intermediate), or structures capable of forming G-quadruplex DNA (for example, predicted in rDNA and telomere sequences).