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. 2014 May 29;10(5):e1004364. doi: 10.1371/journal.pgen.1004364

Figure 7. Disorganized distribution of COLX in exostoses from MC patients.

Figure 7

Alcian Blue and Nuclear Fast Red staining (upper) and immunohistochemical staining of COLX (lower) in exostoses from MC patients (A-C) or an MHE patient (D). Note that the MHE exostosis shows a thin layer of COLX staining at the base of the cartilage cap (D). In contrast, in MC exostoses, the distribution of COLX staining is variable and disorganized, with some exostoses showing expanded COLX domains (A,B), and other showing scatted COLX-positive chondrocytes in the center of the lesion (C). IHC tissue sections were counterstained with hematoxylin. Scale bar  =  1mm; Scale bar in insets  =  50 µm.