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. 2014 May 29;9(5):e97310. doi: 10.1371/journal.pone.0097310

Table 5. Reported access resistance values from in vivo whole-cell patch recordings of neurons in mouse, rat and cat cortex, compared with values from the present study.

Species Age Ra (MΩ) Reference
Mouse P28-34 15–40 (17) [20]
P21-35 55±4 (19) [51]
P28-38 20–60 (12) [52]
5–12 weeks 30–100 (20) [53]
2–8 month 31±17 (21) [54]
Mouse & Rat P21-37 (M), P19-44 (R) 63±(99) [55]
Rat P21-36 47±3 (47) [17]
Adult 119±12 (10) [17]
P28-36 10–75 (48) [56]
P17-24 83+90 (62) [57]
P17-24 60 (16) [58]
3 months 25–60 (21) [59]
P19-26 20±21 (122) [60]
Adult 35±19 (86) This study
Cat Adult 50–200 (25) [10]
Adult 100–250 (37) [61]
Adult 22±15 (109) [36]
Adult 140±44 (12)†† [34]
Adult 70.5±39.7 (40) [62]
Adult 36±19 (83) This study

Note the general tendency for smaller access resistances from recordings on younger animals.

: Recordings limited to Ra<60 MΩ.

††

: Ra taken as the mean of the reported values for the “electrode resistance” corrected with the “residual access resistance” (see table 1 in [34]).