Table 2. List of week/strong oscillator cell line discriminative genes.
Gene name | Gene ID | p-value | Description (DAVID) | KEGG_PATHWAY |
APOBEC3F | 200316 | 1.44E-04 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F | |
AQR | 9716 | 1.13E-05 | aquarius homolog (mouse) | Spliceosome |
ARGLU1 | 55082 | 3.55E-04 | arginine and glutamate rich 1 | |
ATP8B3 | 148229 | 1.32E-04 | ATPase, class I, type 8B, member 3 | |
CAPN6 | 827 | 2.94E-05 | calpain 6 | |
CBX7 | 23492 | 5.13E-05 | chromobox homolog 7 | |
CHD4 | 1108 | 1.56E-05 | chromodomain helicase DNA binding protein 4 | |
CHRNB4 | 1143 | 9.40E-05 | cholinergic receptor, nicotinic, beta 4 | |
CTCF | 10664 | 1.06E-04 | CCCTC-binding factor (zinc finger protein) | |
CTSB | 1508 | 1.19E-04 | cathepsin B | Lysosome, antigen processing and presentation |
DTNB | 1838 | 1.19E-04 | dystrobrevin, beta | |
FBXO17 | 115290 | 6.52E-05 | F-box protein 17 | |
FOXA1 | 3169 | 1.70E-04 | forkhead box A1 | |
GNG11 | 2791 | 9.70E-06 | guanine nucleotide binding protein (G protein), gamma 11 | Chemokine signalling pathway |
GPRASP2 | 114928 | 4.88E-05 | G protein-coupled receptor associated sorting protein 2 | |
HNF4G | 3174 | 3.76E-05 | hepatocyte nuclear factor 4, gamma | Maturity onset diabetes of the young |
HYAL2 | 8692 | 2.82E-05 | hyaluronoglucosaminidase 2 | Glycosaminoglycan degradation |
IFNGR2 | 3460 | 5.83E-05 | interferon gamma receptor 2 (interferon gamma transducer 1) | Cytokine-cytokine receptor interaction, Jak-STAT signalling pathway, Natural killer cell mediated cytotoxicity |
INO80C | 125476 | 1.36E-04 | INO80 complex subunit C | |
KHDRBS3 | 10656 | 5.49E-05 | KH domain containing, RNA binding, signal transduction associated 3 | |
LOXL2 | 4017 | 1.26E-04 | lysyl oxidase-like 2 | |
MAP1B | 4131 | 6.93E-05 | microtubule-associated protein 1B | |
NINJ1 | 4814 | 3.18E-05 | ninjurin 1 | |
NUDT4P1 | 440672 | 1.31E-04 | nudix (nucleoside diphosphate linked moiety X)-type motif 4; nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 | |
PDHX | 8050 | 1.52E-04 | pyruvate dehydrogenase complex, component X | |
PITX2 | 5308 | 9.84E-05 | paired-like homeodomain 2 | TGF-beta signalling pathway |
PPARδ | 5467 | 1.96E-05 | peroxisome proliferator-activated receptor delta | PPAR signalling pathway, Wnt signalling pathway, pathways in cancer, acute myeloid leukemia |
PPFIBP1 | 8496 | 9.75E-05 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | |
RAB6B | 51560 | 6.76E-05 | RAB6B, member RAS oncogene family | |
RBPMS | 11030 | 1.16E-04 | RNA binding protein with multiple splicing | |
RFWD2 | 64326 | 6.53E-05 | ring finger and WD repeat domain 2 | p53 signalling pathway, hsa04120:Ubiquitin mediated proteolysis |
SCN5α | 6331 | 1.06E-04 | sodium channel, voltage-gated, type V, alpha subunit | |
SEC14L2 | 23541 | 7.94E-05 | SEC14-like 2 (S. cerevisiae) | |
SLC37A3 | 84255 | 5.70E-05 | solute carrier family 37 (glycerol-3-phosphate transporter), member 3 | |
SLC39A5 | 283375 | 8.42E-05 | solute carrier family 39 (metal ion transporter), member 5 | |
SNORD58A | 26791 | 3.04E-04 | U58 small nucleolar RNA | |
SNRPA | 6626 | 1.70E-04 | small nuclear ribonucleoprotein polypeptide A | Spliceosome |
SPARC | 6678 | 2.15E-05 | secreted protein, acidic, cysteine-rich (osteonectin) | |
ST3GAL5 | 8869 | 1.02E-04 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | Glycosphingolipid biosynthesis |
STARD8 | 9754 | 1.33E-04 | StAR-related lipid transfer (START) domain containing 8 | |
TBCD | 6904 | 4.37E-05 | tubulin folding cofactor D | |
TSPAN9 | 10867 | 4.31E-05 | tetraspanin 9 | |
USP22 | 23326 | 3.03E-04 | ubiquitin specific peptidase 22 | |
WASF3 | 10810 | 3.81E-06 | WAS protein family, member 3 | Adherens junction, Fc gamma R-mediated phagocytosis |
XYLT2 | 64132 | 4.02E-05 | xylosyltransferase II | Chondroitin sulfate biosynthesis, heparan sulfate biosynthesis |
Raw p-values are derived using moderated t-test between groups of strong versus weak oscillators.