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. Author manuscript; available in PMC: 2014 May 29.
Published in final edited form as: J Med Genet. 2009 Jul 5;47(2):120–125. doi: 10.1136/jmg.2009.067512

Table 3. Logistic regression analysis comparing POAG patients with controls.

Whole group HTG NTG

Predictor variables Odds ratio (95% CI) P value Odds ratio (95% CI) P value Odds ratio (95% CI) P value
MtDNA haplogroup a
H 0.62 (0.26-1.50) 0.292 0.97 (0.43-2.18) 0.934 0.51 (0.20-1.28) 0.151
T 0.42 (0.12-1.48) 0.176 0.65 (0.21-2.00) 0.457 0.37 (0.10-1.45) 0.154
J 3.79 (0.86-16.63) 0.077 1.64 (0.34-8.05) 0.540 4.42 (1.04-18.92) 0.045
U 1.68 (0.50-5.62) 0.401 2.02 (0.62-6.62) 0.246 1.85 (0.53-6.38) 0.332
Others 0.82 (0.24-2.82) 0.757 0.65 (0.19-2.21) 0.490 0.72 (0.21-2.52) 0.609

Compound genotype b
CT/TT 56.52 (5.98-533.78) < 0.001* 9.91 (1.74-56.57) 0.010 29.75 (3.83-231.21) < 0.001*

Our logistic regression models also incorporated the following predictor variables with the controls acting as the reference group: (i) age, (ii) gender, and (iii) maximum IOP, except in the HTG subgroup where maximum IOP was not included;

*

Significant with Bonferroni correction:

a

P < 0.01

b

P < 0.008.