|
NSD3/WHSC1L1
|
54904 |
8 |
0.68 |
Histone methyltransferase |
|
SETDB1
|
9869 |
1 |
0.64 |
Histone methyltransferase |
|
PPFIA1
|
8500 |
11 |
0.62 |
LAR protein-tyrosine phosphatase-interacting protein (liprin) |
|
FRS2
|
10818 |
12 |
0.62 |
Adapter protein (FGFR/MAPK signaling) |
|
APH1A
|
51107 |
1 |
0.6 |
Gamma-secretase complex subunit (Notch pathway) |
|
ERCC5
|
2073 |
13 |
0.6 |
DNA endonuclease (DNA excision repair) |
|
FADD
|
8772 |
11 |
0.58 |
Apoptotic adaptor, candidate driver oncogene |
|
YEATS4
|
8089 |
12 |
0.57 |
NuA4 histone acetyltransferase (HAT) complex subunit |
|
MDM2
|
4193 |
12 |
0.56 |
E3 ubiquitin-protein ligase linked to p53 |
|
KRAS
|
3845 |
12 |
0.56 |
GTPase, proto-oncogene |
|
GTPBP4
|
23560 |
10 |
0.55 |
GTPase, negative regulator of p53 |
|
IKBKB
|
3551 |
8 |
0.54 |
Serine kinase (NF-KB pathway) |
|
DCUN1D1
|
54165 |
3 |
0.53 |
E3 ubiquitin ligase complex subunit, candidate oncogenic driver |
|
RAD52
|
5893 |
12 |
0.53 |
DNA damage repair enzyme |
|
CHD1L
|
9557 |
1 |
0.52 |
DNA helicase involved in DNA damage response |
|
ARNT
|
405 |
1 |
0.51 |
HIF1 complex subunit |
|
PRPF6
|
24148 |
20 |
0.51 |
Spliceosome component (U4/U6-U5 tri-snRNP complex) |
|
PRKCI
|
5584 |
3 |
0.5 |
Serine/threonine kinase (NF-KB pathway) |
|
BCL9
|
607 |
1 |
0.48 |
Trancriptional regulator linked to Wnt signaling |
|
EGFR
|
1956 |
7 |
0.48 |
Receptor tyrosine kinase |
|
RAD51AP1
|
10635 |
12 |
0.48 |
DNA damage response/repair gene |
|
NOTCH2
|
4853 |
1 |
0.47 |
Type 1 transmembrane protein (Notch pathway) |
|
NDUFC2
|
4718 |
11 |
0.47 |
NADH dehydrogenase (Complex I) accessory subunit |
|
GRB7
|
2886 |
17 |
0.47 |
Adapter protein (EGFR/MAPK pathway) |
|
ERC1
|
23085 |
12 |
0.46 |
Regulatory subunit of IKK complex (NF-KB pathway) |
|
RAP1B
|
5908 |
12 |
0.46 |
GTPase, Ras oncogene family |
|
ERBB2
|
2064 |
17 |
0.45 |
Receptor tyrosine kinase |
|
BRD4
|
23476 |
19 |
0.45 |
Epigenetic regulatory gene, chromatin reader |
|
MDM4
|
4194 |
1 |
0.44 |
Nuclear protein, negative regulator of p53 |
|
PIAS3
|
10401 |
1 |
0.42 |
Small ubiquitin-like modifier (SUMO) ligase (JAK/STAT) |
|
PRKAB2
|
5565 |
1 |
0.42 |
AMP-activated protein kinase (AMPK) subunit |
|
CCNE1
|
898 |
19 |
0.41 |
Cell cycle regulator (G1-S) |
|
TPX2
|
22974 |
20 |
0.41 |
Spindle assembly factor, linked to Aurka |
|
PIK3CA
|
5290 |
3 |
0.4 |
Phosphoinositide-3-kinase (PI3K) subunit |
|
CCND3
|
896 |
6 |
0.4 |
Cell cycle regulator (G1-S) |
|
WNK1
|
65125 |
12 |
0.4 |
Serine/threonine kinase, mitotic kinase |
|
RTEL1
|
51750 |
20 |
0.37 |
ATP-dependent DNA helicase (DNA repair) |
|
IGF1R
|
3480 |
15 |
0.36 |
Receptor tyrosine kinase |
|
FGFR3
|
2261 |
4 |
0.3 |
Receptor tyrosine kinase |
|
CDK6
|
1021 |
7 |
0.3 |
Serine/threonine-protein kinase, cell cycle regulator |
