Figure 6. Analysis of peripheral blood functional leukocyte subsets at the different phases of DSS-colitis induction shows altered frequencies of circulating B and CD4⁺ T lymphocytes and CD11b⁺ monocytes between Ncf1* and WT mice.

A) Frequency of CD19⁺ B lymphocytes within total lymphocytes. B) Frequency of CXCR4⁺ cells within CD19⁺ B lymphocytes. C) Frequency of IgM⁻IgD⁻ cells within CD19⁺ B lymphocytes. D) Frequency of CD4⁺ T lymphocytes within CD3⁺ T lymphocytes. E) Frequency of CD25⁺FoxP3⁻ cells within CD4⁺ T lymphocytes. F) Frequency of CD25⁺FoxP3⁺ cells within CD4⁺ T lymphocytes. G) Frequency of Ly6c^hi cells within CD11b⁺ monocytes. H) Frequency of CD68⁺CD11b⁺⁺ cells within CD11b⁺ monocytes. * indicates p<0.05 and ** indicates p<0.01, Mann-Whitney test between Ncf1* and WT; differences between days 0 and 7 are indicated by a: p<0.05, aa: p<0.01, aaa: p<0.001; differences between days 7 and 14 are indicated by b: p<0.05, bb: p<0.01, bbb: p<0.001; differences between days 7 and 21 are indicated by c: p<0.05, cc: p<0.01, ccc: p<0.001; differences between days 14 and 21 are indicated by d: p<0.05, dd: p<0.01, ddd: p<0.001, all Mann-Whitney test. White bars Ncf1*, gray bars WT.