Skip to main content
. 2014 Apr 24;124(6):2785–2801. doi: 10.1172/JCI64784

Figure 8. The duration of AF induced by transesophageal rapid atrial pacing was decreased in Epac1 KO.

Figure 8

(A and B) Transesophageal pacing was performed at a cycle length of 30 ms for 1 minute, and the duration of pacing-induced AF was examined in Epac1 KO and WT (A). The duration of AF was significantly decreased in Epac1 KO compared with WT controls. AF was induced in all WT mice and its duration was 59 ± 3.4 seconds (n = 4). In Epac1 KO, we found that AF was hardly inducible (1.4 ± 1.0 seconds, n = 5, **P < 0.01 versus WT) (B).