Table 3. Selection of the markers significantly different between controls and cases (EO-PE or LO-PE) based on training set.

Type marker	Variable	p-value	FDR	MoM ratio case/control
EO-PE
Blood pressure	MAP	<0.0001	<0.0001	1.10
Amine	Taurine	0.0015	0.07	0.79
Amine	Asparagine	0.0043	0.10	0.84
LO-PE
Blood pressure	MAP	<0.0001	<0.0001	1.07
Amine	Glycylglycine	0.0002	0.01	0.72

Student's t-test was used for statistical analysis. Significance value FDR<15%. EO-PE: early-onset preeclampsia; LO-PE: late-onset preeclampsia; MoM: multiple of the median; FDR: false discovery rate; MAP: mean arterial pressure.