Table 4. Model predicted early preeclampsia detection rate (95% CI) for FPR of 10% with prior risk, MAP, taurine, asparagine and glycylglycine in control and preeclampsia groups.

	Training set		Test set		Validation set
	DR at 10% FPR (95% CI)	AUC	DR at 10% FPR (95% CI)	AUC	DR at 10% FPR (95% CI)	AUC
EO-PE
Prior risk	30 (16–49)	0.74	69 (48–85)	0.92	30 (14–50)	0.73
Prior risk + MAP	55 (37–72)	0.88	81 (58–92)	0.91
Prior risk + taurine	48 (31–66)	0.80	65 (43–82)	0.90
Prior risk + asparagine	36 (22–56)	0.77	70 (48–85)	0.91
Prior risk + MAP + taurine	55 (37–72)	0.88	88 (70–97)*	0.93	55 (36–76)	0.78
Prior risk + MAP + asparagine	55(37–72)	0.87	75 (53–89)	0.91
Prior risk+ MAP + taurine + asparagine	55 (37–72)	0.87	88 (70–97)	0.93
LO-PE
Prior risk	37 (24–53)	0.75	38 (22–55)	0.70	17 (8–35)	0.55
Prior risk + MAP	43 (28–58)	0.81	46 (30–64)*	0.79	17 (8–35)	0.65
Prior risk + glycylglycine	46 (31–60)	0.79	38 (21–59)	0.72
Prior risk + MAP + glycylglycine	53 (37–67)	0.83	42 (27–61)	0.78

DR: detection rate; FPR: false positive rate; MAP: Mean Arterial Pressure; CI: confidence interval; AUC: area under curve, EO-PE: early-onset preeclampsia; LO-PE: late-onset preeclampsia.

*The best model selected for further validation.