Table 1.
Summary of dose volume histogram analysis for GTV, brain stem and ipsilateral cochlea for VS patients
|
GK_1 |
GK_2 |
TB_1 |
TB_2 |
p |
---|---|---|---|---|---|
PTV vol [cm 3 ]: 4.22 ± 2.85 Range: [1.20; 8.50] | |||||
Mean [Gy] |
17.1 ± 0.9 |
17.1 ± 0.8 |
12.9 ± 0.1 |
16.0 ± 0.6 |
a, b, c, d |
D2% [Gy] |
22.7 ± 1.2 |
23.0 ± 0.8 |
13.4 ± 0.2 |
18.8 ± 1.1 |
a, b, c, d |
D98% [Gy] |
12.25 ± 0.0 |
12.25 ± 0.0 |
12.25 ± 0.0 |
12.25 ± 0.0 |
n.s. |
St. dev [Gy] |
2.7 ± 0.3 |
2.8 ± 0.2 |
0.3 ± 0.1 |
1.7 ± 0.3 |
a, b, c, d |
Homogeneity [%] |
51.7 ± 3.5 |
51.8 ± 1.2 |
6.4 ± 1.5 |
35.0 ± 4.9 |
a, b, c, d |
PCI |
0.81 ± 0.03 |
0.78 ± 0.04 |
0.83 ± 0.07 |
0.84 ± 0.04 |
c, d |
PGI |
2.7 ± 0.2 |
2.8 ± 0.2 |
5.1 ± 0.7 |
3.8 ± 0.6 |
a, b, c, d |
DGM [cm] |
0.4 ± 0.1 |
0.4 ± 0.1 |
0.6 ± 0.1 |
0.5 ± 0.1 |
a, b, c, d |
|
Brain stem vol [cm
3
] = 21.50 ± 8.37 Range: [8.69; 32.70] |
||||
D1cm3 [Gy] |
5.1 ± 2.0 |
5.4 ± 2.2 |
5.7 ± 2.1 |
4.8 ± 1.6 |
n.s. |
V8Gy [%] |
1.9 ± 1.7 |
2.3 ± 1.8 |
2.5 ± 1.9 |
1.1 ± 1.0 |
a, b, d |
V10Gy [%] |
0.6 ± 0.5 |
0.8 ± 0.6 |
0.8 ± 0.7 |
0.2 ± 0.2 |
a, b, d |
V12Gy [%] |
0.1 ± 0.1 |
0.2 ± 0.2 |
0.03 ± 0.04 |
0.01 ± 0.01 |
a |
|
Ipsilateral cochlea vol [cm
3
] = 0.10 ± 0.01 Range: [0.02;0.13] |
||||
Mean [Gy] |
6.6 ± 2.9 |
3.3 ± 0.8 |
5.5 ± 2.2 |
4.1 ± 0.9 |
a, b, c |
D0.1cm3 [Gy] |
4.0 ± 1.8 |
1.7 ± 1.0 |
3.1 ± 1.2 |
1.8 ± 0.5 |
a, b, c |
D30% [Gy] | 7.3 ± 3.2 | 3.6 ± 0.8 | 6.2 ± 2.4 | 4.7 ± 1.1 | a, b, c, d |
Statistical significance p: a = GK_1 vs TB_1, b = GKv vs TB_2, c = GK_2 vs TB_1, d = GK_2 vs TV_2; n.s. = not significant. PCI = Paddick Conformity Index, PGI = Paddick Gradient Index, DGM = Dose Gradient measure. Dx% = Dose at x% of the volume.