Table 1.

Sequence variants identified by targeted resequencing of 5.8 Mb in eight cases and eight controls

Annotations	All 16 dogs	Variants in cases	Variants in controls	Case-only variants	Control-only variants
All variants	32,575	29,425	30,253	2,291	3,116
Missense mutations	71	64	61	6	7
Nonsense mutations	0	0	0	0	0
Frame-shift mutations	2	3	3	0	0
Silent coding variants	108	97	89	18	11
UTR variants	22	16	22	0	6
Essential splice site	1	1	1	0	0
Conserved sitesa	1,024	930	908	119	91

^aConserved sites determined by 29 mammals sequence data set [27].