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. 2014 Feb 21;139(1):198–209. doi: 10.1093/toxsci/kfu023

FIG. 6.

FIG. 6.

RNA-seq analysis of E2-regulated and paroxetine-regulated genes in AroER tri-screen cells. (A) Using the data from RNA-seq analysis on RNA preparations from DMSO-treated cells as the references, 1116 of 3166 paroxetine upregulated genes (35%) are present in E2 upregulated genes (3682 genes total). Furthermore, 1441 of 3296 paroxetine downregulated genes (44%) are presented in E2 downregulated genes (3688 genes total). (B) The list of top overlapping genes from comparison of E2 and Paroxetine.