Table 1. Coarse- and fine-grid search results for the best-scoring (and correct) models for uncontaminated simulations, over ten sets of simulated noise.
Simulated association constants: bovine IFN-γ, K 1 = 3.43 × 106; BAF–emerin complex, K 1 = 3.21 × 105, K 2 = 4.23 × 105.
| Search | K 1 | K 2 | Score |
|---|---|---|---|
| Bovine IFN-γ, A + B → AB | |||
| Coarse χ2 | 3.30 × 106 ± 4.8 × 105 | – | 1.53 ± 0.11 |
| Coarse MSMRD | 3.70 × 106 ± 4.8 × 105 | – | 3.74 × 10−7 ± 3.0 × 10−7 |
| Fine χ2 | 3.40 × 106 ± 7.1 × 104 | – | 1.49 ± 0.12 |
| Fine MSMRD | 3.64 × 106 ± 5.2 × 105 | – | 1.82 × 10−11 ± 1.8 × 10−11 |
| BAF–emerin complex, A + B → AB, AB + B → AB 2 | |||
| Coarse χ2 | 3.00 × 105 ± 0.0 | 4.00 × 105 ± 0.0 | 1.17 ± 0.24 |
| Coarse MSMRD | 3.00 × 105 ± 0.0 | 4.00 × 105 ± 0.0 | 1.33 × 10−6 ± 6.8 × 10−7 |
| Fine χ2 | 3.21 × 105 ± 4.5 × 103 | 4.24 × 105 ± 6.9 × 103 | 1.12 ± 0.24 |
| Fine MSMRD | 3.24 × 105 ± 1.3 × 104 | 4.29 × 105 ± 1.9 × 104 | 1.03 × 10−9 ± 6.6 × 10−10 |