Table 3. MARDs (%) for contaminated reconstructions.
Contaminant fraction | Method | I A | I B | I AB | I AB2 |
---|---|---|---|---|---|
Bovine IFN-γ | |||||
0.0000 | LSQ | 0.83 ± 0.2 | 0.28 ± 0.2 | 0.41 ± 0.1 | – |
OPT | 0.27 ± 0.1 | 0.24 ± 0.1 | 0.22 ± 0.1 | – | |
0.0047 | LSQ | 0.53 ± 0.1 | 0.17 ± 0.0 | 0.17 ± 0.0 | – |
OPT | 0.20 ± 0.0 | 0.17 ± 0.0 | 0.09 ± 0.0 | – | |
0.0113 | LSQ | 1.13 ± 0.1 | 0.16 ± 0.0 | 0.34 ± 0.0 | – |
OPT | 0.42 ± 0.0 | 0.16 ± 0.0 | 0.14 ± 0.0 | – | |
0.0231 | LSQ | 2.28 ± 0.1 | 0.17 ± 0.0 | 0.69 ± 0.0 | – |
OPT | 0.83 ± 0.0 | 0.17 ± 0.0 | 0.29 ± 0.0 | – | |
BAF–emerin complex | |||||
0.0000 | LSQ | 0.08 ± 0.0 | 0.64 ± 0.1 | 0.20 ± 0.0 | 0.20 ± 0.0 |
OPT | Not feasible | ||||
0.0047 | LSQ | 2.32 ± 0.0 | 0.08 ± 0.0 | 0.85 ± 0.0 | 0.56 ± 0.0 |
OPT | 1.91 ± 0.0 | 0.08 ± 0.0 | 0.77 ± 0.1 | 0.53 ± 0.0 | |
0.0113 | LSQ | 4.45 ± 0.1 | 0.08 ± 0.0 | 0.90 ± 0.1 | 0.42 ± 0.1 |
OPT | 2.41 ± 0.2 | 0.08 ± 0.0 | 0.56 ± 0.1 | 0.27 ± 0.1 | |
0.0231 | LSQ | 8.72 ± 0.1 | 0.08 ± 0.0 | 1.41 ± 0.1 | 0.60 ± 0.1 |
OPT | 1.31 ± 0.1 | 0.08 ± 0.0 | 0.31 ± 0.1 | 0.21 ± 0.0 |