Table 2. Descriptive statistics of variables MIB-1, PhH3, Mitotic count and IOD. Mean and standard deviation.
| Grade 1 | Grade 2 | Grade 3 | P value* | Overall | |
|---|---|---|---|---|---|
| Number | 8 | 21 | 20 | 49 | |
| MIB-1 count/image field | 181.10 ± 148.83 | 324.06 ± 310.39 | 906.58 ± 647.63 | P < 0.0001 | 538.48 ± 554.30 |
| PhH3 count/image field | 5.48 ± 3.97 | 7.42 ± 11.92 | 30.93 ± 34.80 | P = 0.0010 | 16.70 ± 26.15 |
| Mitotic count/10 HPF | 5.5 ± 4.78 | 9.52 ± 11.47 | 53.25 ± 61.59 | P = 0.0003 | 26.71 ± 45.36 |
| Nuclear IOD | 1398.50 ± 409.88 | 1752.94 ± 797.11 | 2616.78 ± 952.34 | P = 0.0002 | 2047.66 ± 944.16 |
*Independent t-test, comparing combined grades 1 and 2 with grade 3.