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. 2014 May 2;12:31. doi: 10.1186/1741-7007-12-31

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Copyright © 2014 Oboti et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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No display of male-typical behaviors in cGαo^-/-females. (A-D) B6 and cGαo^-/- females display little or no mounting behavior toward male, female, or castrated male intruders (analysis of variance (ANOVA): F_1,56 = 3.339 to 6.286, P = 0.06 to 0.88). B6 and cGαo^-/- male mice show similar mounting behaviors toward female intruders (t-test: P = 0.49 to 0.96). (E,F) Aggression levels toward males remain low in both B6 and cGαo^-/- female mice (ANOVA: F_1,56 = 2.182, P = 0.15 (attack duration)). (G) There are similar intruder investigation times for both B6 and cGαo^-/- female mice (ANOVA: F_1,56 = 0.653, P = 0.42).