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. Author manuscript; available in PMC: 2014 May 30.
Published in final edited form as: Diabetologia. 2012 Sep 28;56(1):60–69. doi: 10.1007/s00125-012-2715-x

Figure 2. Association of family history with T2D risk after adjustment for potential mediators in individuals with full availability of mediators.

Figure 2

All analyses were adjusted for sex and centre. Models were then individually adjusted for each specified risk factor, and all mediators where specified. The proportion of the family-history effect explained by each mediator was calculated as (1-(lnHRadjusted model/ lnHRcrude model)