Table 1.
List of studies considered for the AnLE meta-analysis listed in chronological order.
| No | Study | Patients | Damaged hemisphere | Major disorder | Task | Analysis | Statistics | Foci provided |
|---|---|---|---|---|---|---|---|---|
| 1 | Saygin et al. (2004a) | 29 | LH | Aphasia | Visuo-visual matching of actions | VLSM | t-test | 3 (IFC, S1, caudate) |
| 2 | Buxbaum et al. (2005) | 24 | LH | Apraxia | Detection of action spatial errors | Subtraction | χ2 | 2 (IPC) |
| 3 | Saygin (2007) | 47* | LH | Mixed deficits | Detection of biological motion (whole body) | VLSM | t-test | 2 (IFC, MTC/STC) |
| 4 | Moro et al. (2008) | 28 | 14 LH, 11 RH, 3 Bil | Mixed deficits | Visuo-visual matching of action pictures (upper and lower limbs) | VLSM | BM | 2 (L-IFC, R-IFC) |
| 5 | Pazzaglia et al. (2008a) | 28 | LH | 21 apraxia | Sound-to-picture matching of actions (upper limbs and mouth) | VLSM | BM | 6 (4 IFC, 2 IPC) |
| 6 | Pazzaglia et al. (2008b) | 33* | LH | 21 apraxia | Error detection in action videos | Subtraction and VLSM | χ2 and BM | 3 (IFC) |
| 7 | Weiss et al. (2008) | 16* | LH | 9 apraxia | Detection of sequencing error in action videos | Subtraction | χ2 | 1 (IPC) |
| 8 | Kalénine et al. (2010) | 43 | LH | Mixed deficits | Detection of spatial action errors | VLSM | t-test | 4 (2 MFC, IPC, MTC/STC) |
| 9 | Nelissen et al. (2010) | 13 | LH | 13 aphasia | Error detection in action videos | VBM | Regression | 1 (MTC/STC) |
| 10 | Han et al. (2013) | 77 | 26 LH, 15 RH, 36 Bil | Mixed deficits | Matching of point-light animations with action pictures (whole body) | VLSM | BM | 2 (MFC, MTC/STC) |
| 11 | Kalénine et al. (2013) | 23 | LH | 17 apraxia | Discrimination of means differences between two action videos | VLSM | t-test | 4 (2 IPC, 2 MTC/STC) |
Bil, bilateral; BM, Brunner–Munzell; IFC, inferior frontal cortex (including posterior inferior frontal gyrus and ventral premotor cortex); IPC, inferior parietal cortex (including supramarginal and angular giri and intraparietal sulcus); LH, left hemisphere; MFC, middle frontal cortex (including the middle frontal gyrus and the dorsal aspect of the precentral gyrus, e.g., dorsal premotor and motor cortices); MTC/STC, middle and superior temporal cortex; RH, right hemisphere; S1, primary somatosensory cortex; VLSM, voxel-lesion-symptom mapping. Asterisk indicates that the lesion analysis in the original study was performed only on a subset of patients and the number of patients considered here is that entered into the analysis and not of the study whole sample. Except when otherwise specified, upper limb actions were used as stimuli.