Table II. Tubulin posttranslational modifications, mass changes, and location.
Modification | Δm | Location |
---|---|---|
Tyrosination/detyrosination | ±163.06 Da | C-terminal tail, α-tubulin |
Δ2-Tubulin | −292.10 Da | C-terminal tail, α-tubulin |
Glutamylation | +129.04 Da | C-terminal tail, α- and β-tubulin |
Glycylation | +57.02 Da | C-terminal tail, α- and β-tubulin |
Acetylation | +42.01 Da | α-Tubulin (Lys40) |
Phosphorylation | +79.97 Da | β-Tubulin (Ser441/444) |