Table 1.
Permeability coefficients for metabolites and oxygen (PmO2) in presence of a polyamide membrane (pore size 0.2 μm) with and without mucus layer (200 μm) (n = 2)
Polyamide membrane |
FITC dextran
|
Oxygen
|
||
---|---|---|---|---|
4 kDa | 20 kDa | 150 kDa | ||
With mucus |
2.4 ± 10−6 |
2.5 ± 10−7 |
7.1 ± 10−9 |
2.5 ± 10−4 |
Without mucus | 5.6 ± 10−6 | 4.1 ± 10−7 | 6.5 ± 10−7 | NDa |
aND = not determined.
Data are expressed as cm sec−1. The permeation coefficient was lower in presence of the mucus and with the increase of the FITC dextran kDa.