Table 4. Univariate Logistic Regression Analysis to Identify the Risk Factors for Early-Onset VIPN .

Factor	Odds ratio	95% CI	P value
Male	0.38	0.10 - 1.45	0.16
Age	0.92	0.86 - 0.98	0.013*
Body weight	0.97	0.91 - 1.03	0.31
Aspartate aminotransferase	1.01	0.96 - 1.07	0.59
Alanine aminotransferase	1.05	0.98 - 1.12	0.14
γ-glutamyltranspeptidase	1.00	0.98 - 1.03	0.56
Total bilirubin	3.41	0.25 - 47.00	0.36
Creatinine clearance	1.01	0.99 - 1.03	0.21
Diabetes mellitus requiring medication	0.44	0.045 - 4.39	0.49
Lymphoma type
Diffuse large B-cell lymphoma	1.44	0.38 - 5.45	0.59
Follicular lymphoma	0.48	0.085 - 2.68	0.40
Others	1.20	0.24 - 5.97	0.80
VCR dose	40.81	1.09 - 1,524.04	0.045*
Concomitant use of aprepitant	5.00	1.22 - 20.46	0.025*

*Included in the multivariate logistic regression analysis.