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. 2014 Jul 15;487(100):642–650. doi: 10.1016/j.scitotenv.2014.02.101

Fig. 1.

Fig. 1

Directed acyclic graph for ‘back-calculation’ approach (single metabolite).

Consumptiond = cocaine consumption per 1000 people on day d (mg); Loadd = load of metabolite entering the wastewater system on day d (grammes); Population = size of the population served by the WWTP (millions); Concentrationd = concentration of metabolite in sample of wastewater on day d (ng/l); Flowd = total volume of flow to the wastewater influent on day d (millions of litres); Stability = percentage change in concentration of metabolite in wastewater in the conditions relevant to the study; Excretion = proportion of consumed cocaine that is excreted as the metabolite; MWm = molecular weight of metabolite; MWc = molecular weight of cocaine; ps = proportion of all cocaine mass that is smoked as free base, es = proportion of a dose of cocaine smoked as free base that is excreted as the metabolite; en = proportion of a dose of cocaine consumed by nasal insufflation that is excreted as the metabolite.