Table I. Patients' demographics and clinical characteristics.
Patient | Karyotype/Molecular lesion(s) | FAB subgroup | Age at diagnosis | IDO1 status | CR | Relapse | Alive |
---|---|---|---|---|---|---|---|
UPN #1 | Normal | M2 | 13.0 | Negative | Yes | No | Yes |
UPN #2 | t(8;21) (q22;q22) | M2 | 13.0 | Negative | Yes | No | Yes |
UPN #3 | Normal | M1 | 10.0 | Negative | Yes | No | Yes |
UPN #4 | Normal | M2 | 4.9 | Negative | Yes | No | Yes |
UPN #5 | Normal | M5 | 12.0 | Negative | Yes | No | Yes |
UPN #6 | Normal | M1 | 3.0 | Negative | Yes | No | Yes |
UPN #7 | t(8;21) (q22;q22) | M2 | 9.0 | Negative | Yes | No | Yes |
UPN #8 | Normal | M1/M2 | 1.0 | Negative | Yes | No | Yes |
UPN #9 | Normal | M2 | 15.0 | Negative | Yes | No | Yes |
UPN #10 | N.A. | M1 | 15.4 | Negative | No | Yes | No |
UPN #11 | Normal | N.A. | N.A. | Negative | No | Yes | No |
UPN #12 | FLT3-ITD | U | 6.0 | Negative | No | Yes | Yes |
UPN #13 | Normal | M2 | 3.4 | Negative | Yes | Yes | Yes |
UPN #14 | t(6;9) - FLT3-ITD | M4 | 23.0 | Negative | Yes | Yes | No |
UPN #15 | Normal | M5 | 15.5 | Negative | Yes | Yes | No |
UPN #16 | t(8;21) (q22;q22) | M2 | 11.3 | Negative | Yes | Yes | Yes |
UPN #17 | t(8;21) (q22;q22) | M2 | 9.0 | Negative | Yes | Yes | No |
UPN #18 | FLT3-ITD | N.A. | 14.0 | Negative | N.A. | Yes | No |
UPN #19 | t(9;11)(p22;q23) - MLL-AF9 | M5 | 1.0 | Positive | No | No | No |
UPN #20 | t(10;11) - MLL-AF10 | M5 | 6.0 | Positive | Yes | No | Yes |
UPN #21 | inv(16)(p13q22) | M4 | 16.0 | Positive | Yes | No | No |
UPN #22 | t(8;21) (q22;q22) | M4 | 16.0 | Positive | Yes | No | Yes |
UPN #23 | t(10;11) - MLL-AF10 | M4/M5 | 4.0 | Positive | Yes | No | Yes |
UPN #24 | FLT3-ITD | M4 | 12.3 | Positive | Yes | No | Yes |
UPN #25 | inv(16) (p13q22) | M4 | 17.2 | Positive | Yes | No | Yes |
UPN #26 | t(1;11) - MLL-AF1 | M5 | 0.2 | Positive | Yes | No | Yes |
UPN #27 | inv(16)(p13q22) | M5 | 9.0 | Positive | Yes | No | Yes |
UPN #28 | Normal | M5 | 16.5 | Positive | N.A. | No | No |
UPN #29 | FLT3-ITD | M5 | 7.0 | Positive | No | Yes | No |
UPN #30 | Normal | M5 | 14.1 | Positive | Yes | Yes | No |
UPN #31 | FLT3-ITD | M5 | 15.0 | Positive | Yes | Yes | No |
UPN #32 | Normal | M5 | 0.4 | Positive | Yes | Yes | Yes |
UPN #33 | FLT3-ITD | M5 | 12.3 | Positive | Yes | Yes | No |
UPN #34 | inv(16) (p13q22) | M4 | 13.0 | Positive | Yes | Yes | Yes |
UPN #35 | t(10;11) - MLL-AF10 | M5 | 4.0 | Positive | Yes | Yes | No |
UPN #36 | inv(16) (p13q22) | M4 | 0.8 | Positive | Yes | Yes | Yes |
UPN #37 | FLT3-ITD | M4 | 15.7 | Positive | N.A. | Yes | No |
Legend: UPN = unique patient number; U = undifferentiated AML; N.A. = not available; CR = complete remission; ITD = internal tandem duplication; FAB = French-American-British.