Figure 2. ΔN- and TA isoforms of P63β as well as P73α or P73β isoforms do not exhibit transactivation specificity in yeast.

The indicated P63 (A) or P73 (B) proteins were expressed from stable transformants of isogenic yeast reporter strains and relative transactivation was measured as described in Figure 1B. Average and standard errors of four biological replicates are plotted. In panel A, the light gray bars indicate results obtained with the P63 proteins that were presented in Figure 1 and are included here to facilitate the comparison of results obtained with the P63β isoforms. Additional results are presented in Table S2 and S3.