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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(4):940–946. doi: 10.1016/j.ijrobp.2013.12.001

Figure 4.

Figure 4

White blood cell counts are severely affected by proton radiation exposure. Blood was collected prior to radiation (pre-irradiation), until 30 days post-irradiation. 2 Gy data were unavailable at days 21 and 30 due to 0% animal survival. Data were normalized to pre-irradiation counts and are reported as a fraction of control. The dotted line indicates the pre-irradiation count of 1.0. ANOVA was used to determine the dose response for each time-point (with three doses; if only two dose groups were available, a student’s t-test was used). Significance is reported for *p < 0.05, **p < 0.005, and ***p < 0.001. A statistically significant dose dependent decrease in WBC (A), lymphocyte (B), neutrophil (C), monocyte (D), and eosinophil (E) counts was observed at 0.5, 7, and 13 days post-irradiation.