Table 4.
Mayo central |
||||||
---|---|---|---|---|---|---|
HER2 negative | HER2 positive | |||||
IEO central | IHC neg / FISH neg | IHC equ / FISH neg | IHC equ / FISH equ | IHC equ / FISH pos | IHC pos / FISH pos | Total |
HER2 negative | ||||||
IHC neg / FISH neg | 3 | 3 | -- | 1 | -- | 7 |
IHC equ / FISH neg | -- | 1 | -- | 1 | -- | 2 |
IHC equ / FISH equ | -- | -- | -- | 2 | 1 | 3 |
HER2 positive | ||||||
IHC equ / FISH pos | -- | 1 | -- | 1 | 3 | 5 |
IHC pos / FISH pos | -- | -- | -- | -- | 6 | 6 |
Total | 3 | 5 | 0 | 5 | 10 | 23 |
IHC immunohistochemical, HER2 human epidermal growth factor receptor 2, FISH fluorescent in situ hydridization, Mayo Mayo Clinic central laboratory, IEO European Institute of Oncology central laboratory, neg negative, equ equivocal, pos positive