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. Author manuscript; available in PMC: 2014 Oct 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Jun 26;272(2):299–305. doi: 10.1016/j.taap.2013.06.016

Table 1.

Tumor incidence in 12- and 18-month old mice

Group 12-month old 18-month old
Mouse number Tumor incidence (%) Mouse number Tumor incidence (%)
WT 16 0 18 0
FXR−/− 16 56.3 20 100
SHPTg 16 0 18 0
FXR−/−/SHPTg 14 64.3 18 100

Note: Mice in each group were sacrificed at 12 and 18 months of age with n=14–20 per group.