Table 5B. Summary of OS Stratified by TERT promoter and IDH1/2 Mutational Status in Grades III and IV.
OS in months (95% CI) | 1 year OS (95% CI) | 2 year OS (95% CI) | 5 year OS (95% CI) | 10 year OS (95% CI) | |||
---|---|---|---|---|---|---|---|
TERT MUT / IDH WT | 187 | 168 | 11.5 (10.0, 14.0) |
48.5% (41.0%, 55.7%) |
16.4% (11.3%, 22.4%) |
1.9% (0.5%, 5.5%) |
1.0% (0.1%, 4.4%) |
TERT WT / IDH WT | 50 | 37 | 17.2 (10.5, 26.2) |
61.4% (45.9%, 73.7%) |
35.9% (21.8%, 50.2%) |
10.4% (3.0%, 23.2%) |
10.4% (3.0%, 23.2%) |
TERT WT / IDH MUT | 82 | 40 | 56.9 (38.8, 66.2) |
87.8% (77.8%, 93.5%) |
76.2% (63.9%, 84.8%) |
44.3% (30.6%, 57.1%) |
30.3% (18.0%, 43.6%) |
TERT MUT / IDH MUT | 42 | 18 | 125.2 (54.7, 197.2) |
92.2% (77.8%, 97.4%) |
83.2% (66.2%, 92.1%) |
62.7% (43.4%, 77.1%) |
53.9% (33.9%, 70.2%) |