Figure 4. AR-V attenuates androgen and enzalutamide modulation of cell growth.
A. AR-V7 knockdown enhances the response of 22Rv1 cells to androgen and enzalutamide modulation of cell growth. B. Enzalutamide inhibition of 22Rv1 tumor growth becomes more pronounced after AR-V7 knockdown. Data are expressed as % of inhibition by enzalutamide. *, P < 0.05. Enzalutamide (Enz), 10 mg/kg/day. n = 8.