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editorial

. 2014 Apr 2;5(6):1683–1698. doi: 10.18632/oncotarget.1849

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Copyright: © 2014 Pollock et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. U2OS cells were treated with vehicle or 5 ppm of ST362 or 5 ppm MEB55 for 6 hrs. Total RNA was extracted and analyzed by expression array. Results of two independent experiments are displayed as a Heatmap of genes differentially expressed in U2OS cells treated with MEB55 or with ST362 for 6 hrs. Genes that were ±2 fold p≤0.05 upregulated are shown in red and down regulated transcripts are shown in green. A representative list of individual genes at 6 hrs (±2 fold p≤0.05) is presented in Table 2 and at 24 hrs in Table S1. B-H qRT-PCR analysis of representative genes in A. I. A protein network of top upregulated genes in response to MEB55 and ST362 was constructed using the Ingenuity software.

A. U2OS cells were treated with vehicle or 5 ppm of ST362 or 5 ppm MEB55 for 6 hrs. Total RNA was extracted and analyzed by expression array. Results of two independent experiments are displayed as a Heatmap of genes differentially expressed in U2OS cells treated with MEB55 or with ST362 for 6 hrs. Genes that were ±2 fold p≤0.05 upregulated are shown in red and down regulated transcripts are shown in green. A representative list of individual genes at 6 hrs (±2 fold p≤0.05) is presented in Table 2 and at 24 hrs in Table S1. B-H qRT-PCR analysis of representative genes in A. I. A protein network of top upregulated genes in response to MEB55 and ST362 was constructed using the Ingenuity software.