Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 May 23;11:94. doi: 10.1186/1742-2094-11-94

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Italiani et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Levels of IL-18, IL-18BP and free IL-18 in serum of ALS patients. Levels of IL-18 (A) and of IL-18BP (B) were measured by ELISA in sera from sporadic ALS patients (sALS) in comparison to NHS. Patients were also grouped depending on the form of the disease. Based on the law of mass action, the concentration of free IL-18 (not bound and inhibited by IL-18BP) was calculated from total IL-18 and total IL-18BP concentrations [30,31](C). Statistical significance was calculated using the Mann–Whitney U-test. ALS, amyotrophic lateral sclerosis; BF, bulbar form; LL, lower limbs; NHS, normal healthy subjects; UL, upper limbs.