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. 2014 May 20;7:38. doi: 10.1186/1756-6606-7-38

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Copyright © 2014 Lu et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Anandamide (AEA) postpones AISS induction at hippocampal GABAergic neurons. AISS is induced under the control and subsequent use of AEA (5 μM)I after the first round of AISS disappears for 6 minutes, a time interval similar to Figure 1. A) shows AISS induction under the control (top trace) and in presence of AEA (bottom trace). Calibration bars are 20 mV and 10 seconds. B) shows the dynamical changes in threshold potentials under the control (blue symbols) and in presence of AEA (red symbols). C) illustrates the number of spikes needed for AISS onset under the control (blue bar) and in presence of AEA (red bar; asterisk, p < 0.01, n = 9).