Table 4.
Patient-Level Diagnostic Accuracy of Cardiac CT–Myocardial Perfusion Imaging (CT-MPI) for and CT Acute Coronary Syndrome
| Imaging Protocol | No. of Patients | Sensitivity | Specificity | Positive Predictive Value | Negative Predictive Value | Receiver Operator Curve Area Under the Curve |
|---|---|---|---|---|---|---|
|
| ||||||
| Cardiac CT | 105 | 100 (66–100) | 89 (80–94) | 45 (23–69) | 100 (96–100) | 94 (91–98) |
| CT-MPI | 105 | 33 (7–70) | 100 (96–100) | 100 (29–100) | 94 (88–98) | 67 (50–83) |
| Cardiac CT plus CT-MPI | 105 | 33 (7–70) | 100 (96–100) | 100 (29–100) | 94 (88–98) | 67 (50–83) |
| > 50% stenosis | 20 | 33 (7–70) | 100 (72–100) | 100 (29–100) | 65 (38–86) | 67 (50–0.83) |
| ≤ 50%a | 85 | 100 | NA | NA | 100 | NA |
Note—Data are percentage (95% CI). NA = not applicable.
a
Because no acute coronary syndrome occurred in the combined cardiac CT plus CT-MPI group with ≤ 50% stenosis, specificity, positive predictive value, receiver operating characteristic, and 95% CI could not be determined.