Table 2. Summary of results for selected SNPs showed associations with risk of breast cancer.
| Loci | Chr:positiona | LincRNA:positiona | MAF (case, control) | OR (95%CI)b | P value |
| Eastern Chinese (Suzhou) | |||||
| rs12325489(C>T) | 16q:50864577 | ENST00000515084 exon 1 | T = 0.29, 0.38 | 1.49 (1.31–1.68) | <1.0×10−7 |
| rs2272901(C>T) | 6q:149581466 | uc003qmi.2 exon 2 | T = 0.41, 0.41 | 1.09 (0.96–1.25) | 0.182 |
| rs532367(A>G) | 6q:149584491 | uc003qmi.2 exon 3 | G = 0.45, 0.46 | 1.02 (0.90–1.16) | 0.679 |
| rs603092(G>A) | 6q:149584784 | uc003qmi.2 exon 3 | A = 0.13, 0.14 | 1.12 (0.93–1.36) | 0.469 |
| rs17841343(G>A) | 16q:48512623 | ENST00000506071 exon 1 | A = 0.21, 0.21 | 0.98 (0.84–1.15) | 0.915 |
| rs4785367(T>C) | 16q:48513695 | ENST00000506071 exon 1 | C = 0.28, 0.30 | 1.11 (0.96–1.28) | 0.071 |
| rs2278016(T>C) | 16q:50674510 | uc002egu.2 exon 1 | C = 0.13, 0.13 | 0.97 (0.80–1.18) | 0.882 |
| rs3815784(C>T) | 16q:50675154 | uc002egu.2 exon 1 | T = 0.07, 0.06 | 0.78 (0.60–1.02) | 0.066 |
| rs1362378(A>C) | 16q:50863415 | ENST00000515084 exon 1 | C = 0.45, 0.45 | 1.01 (0.89–1.15) | 0.943 |
| rs3803662(T>C) | 16q:51143842 | NR_033920 exon 1 | C = 0.35, 0.35 | 0.96 (0.83–1.10) | 0.913 |
| rs10750417(G>A) | 11q:128987385 | ENST00000511090 exon 1 | A = 0.21, 0.20 | 0.92 (0.79–1.09) | 0.313 |
| rs10894115(C>G) | 11q:129070287 | uc001qfd.1 exon 1 | G = 0.23, 0.22 | 0.91 (0.78–1.06) | 0.148 |
| rs1814343(T>C) | 11q:129070462 | uc001qfd.1 exon 1 | C = 0.39, 0.39 | 1.00 (0.88–1.15) | 0.915 |
| rs1814344(T>C) | 11q:129070626 | uc001qfd.1 exon 1 | C = 0.24, 0.23 | 0.98 (0.84–1.14) | 0.513 |
| rs4937447(C>T) | 11q:129070761 | uc001qfd.1 exon 1 | T = 0.47, 0.45 | 0.88 (0.77–1.01) | 0.146 |
| rs10894116(G>A) | 11q:129072920 | uc001qfd.1 exon 1 | A = 0.16, 0.18 | 1.09 (0.91–1.29) | 0.358 |
| Southern Chinese (Guangzhou) | |||||
| rs12325489(C>T) | 16q:50864577 | ENST00000515084 exon 1 | T = 0.29, 0.39 | 1.52 (1.31–1.79) | <1.0×10−7 |
| Northern Chinese (Harbin) | |||||
| rs12325489(C>T) | 16q:50864577 | ENST00000515084 exon 1 | T = 0.26, 0.36 | 1.58 (1.34–1.82) | <1.0×10−7 |
| Pooled analysis | |||||
| rs12325489(C>T) | 16q:50864577 | ENST00000515084 exon 1 | T = 0.28, 0.37 | 1.51 (1.37–1.68) | <1.0×10−7 |
a
Data of position based on the International HapMap project (Rel 27 PhaseII+III, Feb09, on NCBI B36 assembly, dbSNP b126).
b
Data were calculated by unconditional logistic regression, adjusted for age, BMI, and family history of cancer.