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. 2014 May 15;12:130. doi: 10.1186/1479-5876-12-130

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Copyright © 2014 Zhang et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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NGF improves the locomotor activity of SCI rats. A. The BBB scores and B. incline plane test of sham, SCI group and SCI rat treated with NGF group. * P < 0.05 versus the SCI group, and ** P < 0.01 versus the SCI group, n = 6. C. Representative footprints obtained from each group at 14 days after SCI show that NGF treated rats display fairly consistent weight-support plantar stepping and very little toe dragging. In contrast, vehicle control rats show consistent dorsal stepping and extensive toe dragging.