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. 2014 May 20;10:29. doi: 10.1186/1744-8069-10-29

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Copyright © 2014 Barragán-Iglesias et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Spinal nerve injury increases the expression of P2Y₆and P2Y₁₁: Blockade by minocycline or fluorocitrate. Effect of the repeated intrathecal administration of minocycline (Mino, panel A and B) or fluorocitrate (Fluo, panel C and D) in spinal nerve injury-induced increased expression of P2Y₆ and P2Y₁₁ receptors in the ipsilateral dorsal spinal cord. Data were normalized against β-actin and are expressed as the mean ± S.E.M. of 3 independent rats. * Significantly (p < 0.05) different from the naïve (N) group and ^# significantly (p < 0.05) different from the spinal nerve ligated (SNL) group, as determined by one-way analysis of variance followed by the Student-Newman-Keuls test.