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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Cortex. 2013 Dec 20;55:182–191. doi: 10.1016/j.cortex.2013.12.004

Table 4.

Candidate Gene Associations with LSA-Derived Variables.

Gene Class Phenotype Gene SNP Chromosome Beta p-value Group
Verbal Fluency Overall Vector Length DISC1 rs6675281 1 0.022 0.033 All Controls
Verbal Fluency Average Vector Length SLC6A3 rs6350 5 4.0E-03 0.029 All Controls
Verbal Fluency Average Vector Length DISC1 rs12133766 1 −0.0093 0.018 Male Controls
Verbal Fluency1 Average Vector Length DISC1 rs12133766 1 −0.0085 0.049 Male Probands
Verbal Fluency Cohesion (WS = 1) DISC1 rs12133766 1 −0.029 0.028 Male Controls
Episodic Memory Average Vector Length WWC1 rs17551608 5 −0.0028 0.045 All Controls
Episodic Memory Number of Valid Words WWC1 rs17551608 5 1.38 0.011 All Controls
Episodic Memory Number of Valid Words WWC1 rs17551608 5 1.73 0.0062 Female Controls
Episodic Memory Cohesion (WS = 2) WWC1 rs3733980 5 −0.013 0.043 Male Controls
Episodic Memory Number of Valid Words KIAA0319 rs807534 6 −1.45 0.032 All Controls
Episodic Memory Number of Valid Words KIAA0319 rs807534 6 −1.74 0.032 Female Controls
Episodic Memory Number of Valid Words KIAA0319 rs807534 6 −1.67 0.041 Female Siblings
Episodic Memory Number of Valid Words KIAA0319 rs807541 6 −1.35 0.028 Female Controls
Episodic Memory Overall Vector Length KIAA0319 rs4576240 6 0.041 0.046 Male Controls
Episodic Memory Overall Vector Length CLSTN2 rs10804675 3 0.031 0.019 Male Controls
Episodic Memory Overall Vector Length CLSTN2 rs10804675 3 −0.028 0.0026 Female Controls
Episodic Memory Average Vector Length CLSTN2 rs10804675 3 −0.0033 0.015 Female Controls
Episodic Memory Cohesion (WS = 1) CLSTN2 rs10804675 3 −0.015 0.010 Female Controls
Episodic Memory Cohesion (WS = 2) BDNF rs6265 11 −0.014 0.023 Male Controls
Episodic Memory Number of Valid Words ZNF804A rs1366842 2 1.31 0.042 Male Controls
Episodic Memory Number of Valid Words ZNF804A rs1366842 2 −1.12 0.033 Male Probands
Episodic Memory Average Cosine ZNF804A rs1366842 2 −0.0064 0.042 Female Controls
Episodic Memory Cohesion (WS = 3) HTR2A rs6314 13 −0.017 0.033 Female Controls
Episodic Memory Cohesion (WS = 1) DCDC2 rs2274305 6 −0.013 0.035 Male Controls
Language Cohesion (WS = 2) DYX1C1 rs600753 15 0.010 0.0062 All Controls
Language Cohesion (WS = 2) DYX1C1 rs600753 15 0.011 0.040 Male Controls
Language Cosine to ‘Animal’ DYX1C1 rs600753 15 0.0051 0.048 (0.055) All Controls
Language Cosine to ‘Animal’ DYX1C1 rs600753 15 −0.0082 0.022 Female Controls
Language Cohesion (WS = 1) ATP2C2 rs2303853 16 0.033 0.032 Male Controls
Processing Speed Average Cosine ATRNL1 rs10885721 10 −0.0053 0.013 All Controls
Processing Speed Average Cosine ATRNL1 rs10885721 10 0.0065 0.038 Female Controls
Processing Speed Average Cosine PKNOX1 rs234781 21 0.010 0.0063 All Controls
Processing Speed Average Cosine PKNOX1 rs234781 21 0.011 0.039 Female Controls
Processing Speed Average Vector Length PDE1C rs3213709 7 0.0027 0.032 All Controls
Processing Speed Cohesion (WS = 1) PDE1C rs3213709 7 0.010 0.025 All Controls
Processing Speed Cohesion (WS = 1) PDE1C rs2302450 7 0.011 0.017 All Controls
Processing Speed Cohesion (WS = 1) PDE1C rs2302450 7 0.020 0.0024 Male Controls
Processing Speed Cohesion (WS = 1) SPATA7 rs3179969 14 0.011 0.010 All Controls
Processing Speed Cohesion (WS = 1) SPATA7 rs3179969 14 0.018 0.0050 Male Controls
1

Significant replication sample results are given in italics.