Table 3.
Multivariate analysis of predictive factors for RFS and PFS
| RFS | PFS | ||||
|---|---|---|---|---|---|
|
|
|||||
| Variables | Categories | Hazard ratio* (95% CI) | p value | Hazard ratio* (95% CI) | p value |
| Hydronephrosis | Yes vs. No | 2.406 (0.733–7.896) | 0.148 | 1.419 (0.305–6.599) | 0.656 |
| Multifocality of tumours | Yes vs. No | 0.957 (0.436–2.097) | 0.912 | N/A | N/A |
| T stage on initial TUR | Ta, T1 | N/A | N/A | 2.461 (0.820–7.385) | 0.108 |
| T stage on re-TUR | T0, Ta, CIS, T1 | 1.776 (1.279–2.464) | 0.001 | 2.114 (1.163–3.845) | 0.014 |
| Immediate intravesical chemotherapy | Yes vs. No | 0.854 (0.370–1.970) | 0.711 | N/A | N/A |
| Regimen of intravesical BCG therapy | Induction alone vs. maintenance | 0.165 (0.064–0.424) | < 0.001 | 0.097 (0.017–0.542) | 0.008 |
*
Hazard ratio according to Cox regression analysis. TUR: transurethral resection; RFS: recurrence-free survival; PFS: progression-free survival; BCG: bacillus Calmette-Guérin.