Table 1.

Clinical presentation – first cardiac medical examination

Case n°	Age at diagnosis	Clinical signs at first examination	ECG and Holter-ECG	Echocardiography at diagnosis	Cardiac surgery
1	2 months	Arrhythmia	Atrial and ventricular ectopic beats	Multiple rhabdomyomas	No
			WPW Syndrome
2	1 month	Heart murmur	Normal	Multiple rhabdomyomas	No
3	2 months	Heart murmur	Widened QRS	Multiple rhabdomyomas	No
4	Fetal	No symptoms but RVOT obstruction	Normal	Multiple rhabdomyomas	No
5	1 day	Heart murmur	Normal	Multiple rhabdomyomas	No
		LV obstruction
6	1 day	Heart murmur	Normal	Multiple rhabdomyomas	No
7	Fetal	No symptoms	RV hypertrophy	Lobulated mass in LV	No
8	Fetal	No symptoms	Normal	Multiple rhabdomyomas	No
9	1 month	Heart murmur	RV hypertrophy	Lobulated mass in IVS	No
10	1 day	Cyanosis	Atrial and ventricular ectopic beats	Multiple rhabdomyomas	No
		LV obstrution
11	2 months	No symptoms	Atrial ectopic beats	Multiple rhabdomyomas	No
12	1 months	No symptoms	RV overload signs	Multiple rhabdomyomas	No
13	Fetal	Heart failure Cyanosis	Atrial and ventricular ectopic beats	Multiple rhabdomyomas	Yes
14	1 day	Heart murmur	Normal	Multiple rhabdomyomas	No
15	7 months	Heart murmur	Atrial and ventricular ectopic beats	Multiple rhabdomyomas	No
			WPW Syndrome
16	1 day	No symptoms	Incomplete right bundle branch block	Multiple rhabdomyomas	No
17	9 months	Heart murmur	Normal	Multiple rhabdomyomas	No
18	1 day	Arhythmia	Atrial and ventricular ectopic beats	Multiple rhabdomyomas	No
19	Fetal	No symptoms (hypokinesia)	Normal	Multiple rhabdomyomas	No
20	4 months	Heart murmur	Ventricular ectopic beats and RV overload signs	Multiple rhabdomyomas	No
21	Fetal	No symptoms	WPW Syndrome	Multiple rhabdomyomas	No
			IVS overload signs
22	3 days	Heart murmur	Normal	Multiple rhabdomyomas	No
23	11 months	No symptoms	RV overload signs	Multiple rhabdomyomas	No
24	5 months	No symptoms	Atrial and ventricular ectopic beats	Multiple rhabdomyomas	No
25	1 day	Heart murmur	Normal	Multiple rhabdomyomas	No
26	9 months	Seizures	Normal	Multiple rhabdomyomas	No
27	Fetal	No symptoms	Normal	Multiple rhabdomyomas	No
28	2 months	No symptoms	Normal	Multiple rhabdomyomas	No
29	Fetal	No symptoms	RV overload signs	Multiple rhabdomyomas	No
30	Fetal	Heart murmur	Normal	Multiple rhabdomyomas	No
31	7 days	Heart murmur	Normal	Multiple rhabdomyomas	No
32	21 days	No symptoms	RV hypertrophy	Multiple rhabdomyomas	No
33	Fetal	Heart murmur	Ventricular ectopic beats	Multiple rhabdomyomas	No